1,500 ventilators a week to roll off UK production lines by May, say manufacturers

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"1">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>At least 1&comma;500 ventilators a week could be rolling off British production lines by the end of the month to help in the fight against Covid-19&comma; a leading manufacturing group has said&period;<&sol;p>&NewLine;<p>The NHS &lpar;Britain&&num;8217&semi;s health service&rpar; is set to get 30 new ventilators next week with the British Government promising &OpenCurlyDoubleQuote;hundreds” more to follow&period;<&sol;p>&NewLine;<p>It is thought at least 30&comma;000 ventilators will be needed to cope with the peak of the coronavirus pandemic there&comma; with manufacturing companies including Dyson&comma; Siemens and Rolls-Royce involved in a drive to produce more&period;<&sol;p>&NewLine;<p>There are 8&comma;000 ventilators currently being used across the NHS in the UK&comma; helping to treat the most <a href&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;covid-19-no-immediate-prospect-of-mass-nhs-staff-testing&sol;">severely affected Covid-19 patients<&sol;a>&period;<&sol;p>&NewLine;<p>The devices take over a patient’s breathing function while they are sedated&comma; pushing air into the lungs and giving time to fight the infection and recover&period;<&sol;p>&NewLine;<p>Earlier this week&comma; Chris Hopson&comma; chief executive of NHS Providers&comma; which represents healthcare trusts&comma; said it was clear ventilator numbers needed to &OpenCurlyDoubleQuote;significantly increase”&period;<&sol;p>&NewLine;<p>A key consortium which answered the Government’s call to help meet demand for the devices&comma; said on Thursday it would be &OpenCurlyDoubleQuote;scaling up” production over coming weeks&comma; aiming to make 1&comma;500 machines a week&comma; by early May&period;<&sol;p>&NewLine;<p>The announcement comes as another group of scientists&comma; manufacturers and clinicians have unveiled plans for a non-invasive alternative to the ventilator&comma; called Exovent&comma; which is a reinvention of iron lung-technology&comma; used to treat polio patients&period;<&sol;p>&NewLine;<p>Project clinicians hope the device’s simple design&comma; which will shortly be under-going clinical trials&comma; means thousands could be made &OpenCurlyDoubleQuote;very quickly and cheaply” with off-the-shelf parts&period;<&sol;p>&NewLine;<p>The Ventilator Challenge UK group which includes Rolls-Royce&comma; Airbus&comma; and leading Formula One racing teams&comma; said on Monday it had received a formal order to provide the NHS with 10&comma;000 devices&period;<&sol;p>&NewLine;<p>The consortium has used its considerable design and building resources to help deliver two different models&comma; under the codenames Project Oyster and Project Penguin&comma; in a little over two weeks&period;<&sol;p>&NewLine;<p>Project Oyster has involved making slight tweaks to an existing design by Oxfordshire-based firm Penlon&comma; aimed at speeding up the assembly process&period;<&sol;p>&NewLine;<p>The consortium is also lending its manufacturing muscle to increasing production of a device called the ParaPac ventilator&comma; made by Luton-based Smiths Medical&comma; under Project Penguin&period;<&sol;p>&NewLine;<p>Dick Elsy&comma; who is leading the consortium&comma; said&colon;<em> &OpenCurlyDoubleQuote;To provide some context&comma; Penlon and Smiths ordinarily have combined capacity for between 50 and 60 ventilators per week&period;<&sol;em><&sol;p>&NewLine;<p><em>&OpenCurlyDoubleQuote;However&comma; thanks to the scale and resources of the wider consortium&comma; we are targeting production of at least 1&comma;500 units a week of the Penlon and Smiths models combined within a matter of weeks&period;”<&sol;em><&sol;p>&NewLine;<p>He added that engineers were working round the clock on what were &OpenCurlyDoubleQuote;intricate and highly complex devices”&comma; balancing speed with the need to ensure patients’ safety&period;<&sol;p>&NewLine;<p>Work to re-engineer parts for the Smiths-made ventilator has been carried out by the Williams racing team&comma; with about 50 people involved remotely or working from its factory in Grove&comma; Oxfordshire&period;<&sol;p>&NewLine;<p>Meanwhile it is hoped the Exovent device&comma; which involves the UK’s Marshall Aerospace &amp&semi; Defence Group and Warwick Manufacturing Group&comma; will be ready for clinical trials within days&comma; with two hospitals agreeing to help test it and talks with a third on-going&period;<&sol;p>&NewLine;<p>Once trials are completed&comma; the results will be presented to the Medicines and Healthcare products Regulatory Agency &lpar;MHRA&rpar;&comma; which regulates use of all such devices in the UK&period;<&sol;p>&NewLine;<p>Dr Malcolm Coulthard &comma; the project’s leading clinician&period; said&colon; <em>&OpenCurlyDoubleQuote;As soon as we looked into the science and the literature it immediately became apparent that this will allow us to produce less-invasive devices than the conventional units in current use&comma; possibly better for patients’ hearts&comma; at a fraction of the price&comma; using off-the-shelf parts&period;”<&sol;em><&sol;p>&NewLine;<p>Backing the project&comma; professor of clinical genetics at Newcastle University&comma; Sir John Burn said&colon; <em>&OpenCurlyDoubleQuote;The Exovent team has cleverly adapted the old concept of the iron lung which was used for treating polio&period;<&sol;em><&sol;p>&NewLine;<p><em>&OpenCurlyDoubleQuote;This device is cheap&comma; simple and it will work&period; I am convinced it provides a real alternative and is worthy of support&period;”<&sol;em><&sol;p>&NewLine;<p>Last month&comma; Dyson said it had received an order from Prime Minister Boris Johnson&comma; who has coronavirus&comma; to build 10&comma;000 of its own CoVent design&period;<&sol;p>&NewLine;<p>Production of other existing devices made by firms Diamedica&comma; in Barnstaple&comma; and Breas Medical&comma; in Stratford-upon-Avon&comma; Warwickshire&comma; have also been scaled up&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68e231d3620a8">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; 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