AstraZeneca asks US drug regulator to authorise Covid antibody treatment

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>AstraZeneca has asked the US Food and Drug Administration to authorise the emergency use of an antibody treatment to prevent Covid-19&period;<&sol;p>&NewLine;<p>The Anglo-Swedish drug maker&comma; which developed one of the first Covid vaccines&comma; said the treatment&comma; known as AZD7442&comma; would be the first long-acting antibody combination to receive an emergency use authorisation for Covid-19 prevention&period;<&sol;p>&NewLine;<p>The treatment may help protect people whose immune systems do not respond adequately to vaccination&comma; AstraZeneca said&period;<&sol;p>&NewLine;<p>Late-stage human trials showed that AZD7442 reduced the risk of developing symptomatic Covid-19 by 77&percnt;&period;<&sol;p>&NewLine;<p>More than three-quarters of the participants had suppressed immune systems and other conditions that made them more susceptible to severe disease&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Vulnerable populations such as the immunocompromised often aren’t able to mount a protective response following vaccination and continue to be at risk of developing Covid-19&comma;” Mene Pangalos&comma; AstraZeneca’s executive vice president for pharmaceutical research&comma; said in a statement&period;<&sol;p>&NewLine;<p><&excl;--Ads1--><&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;With this first global regulatory filing&comma; we are one step closer to providing an additional option to help protect against Covid-19 alongside vaccines&period;”<&sol;p>&NewLine;<p>US demand for antibody treatments soared over the summer&comma; particularly in states like Florida&comma; Louisiana and Texas&comma; where hospital admissions among unvaccinated patients threatened to overwhelm the health care system&period;<&sol;p>&NewLine;<p>The drugs are laboratory-made versions of virus-blocking antibodies that help fight infections&period; The treatments help the patient by supplying concentrated doses of one or two antibodies&period;<&sol;p>&NewLine;<p>The main antibody treatment being used in the US is Regeneron’s dual-antibody cocktail&period; The FDA has also authorised the Regeneron product as protection for high-risk people against severe Covid-19&period;<&sol;p>&NewLine;<p>Meanwhile&comma; Johnson &amp&semi; Johnson asked the FDA to allow extra shots of its Covid-19 vaccine as the US government moves towards expanding its booster campaign to millions more vaccinated Americans&period;<&sol;p>&NewLine;<p><&excl;--Ads2--><&sol;p>&NewLine;<p>J&amp&semi;J said it filed a request with the FDA to authorise boosters for people 18 and older who had previously received the company’s one-shot vaccine&period;<&sol;p>&NewLine;<p>While the company said it submitted data on different booster intervals&comma; ranging from two to six months&comma; it did not formally recommend one to regulators&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68cd4d0cab736">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; function &lpar;&rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;if &lpar; false &equals;&equals;&equals; &lpar; window&period;isWatlV1 &quest;&quest; false &rpar; &rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&sol;&sol; Use Aditude scripts&period;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings &equals; window&period;tudeMappings &vert;&vert; &lbrack;&rsqb;&semi;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings&period;push&lpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;divId&colon; 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