AstraZeneca halts work on lung drug

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p><a href&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2010&sol;12&sol;astrazeneca-halts-work-on-lung-drug&period;jpg"><img class&equals;"alignnone size-full" title&equals;"AstraZeneca has halted developments on a lung treatment drug" src&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2010&sol;12&sol;min-astrazeneca-halts-work-on-lung-drug&period;jpg" alt&equals;"AstraZeneca has halted developments on a lung treatment drug"&sol;><&sol;a><&sol;p>&NewLine;<p>Pharmaceuticals giant AstraZeneca has revealed its second drugs blow in a week as it said it had dropped development of one of its experimental treatments&period;<&sol;p>&NewLine;<p>The group said its motavizumab drug to prevent serious lung disease in infants had been discontinued&comma; leading to a 445 million US dollar &lpar;£287&period;2 million&rpar; accounting charge&period;<&sol;p>&NewLine;<p>The news follows AstraZeneca&&num;8217&semi;s disappointment last week over a further delay in winning approval from US regulators for its heart medicine Brilinta&period;<&sol;p>&NewLine;<p>The US Food and Drug Administration &lpar;FDA&rpar; wanted further analysis of research into Brilinta &&num;8211&semi; a blood-thinning pill &&num;8211&semi; before clearing the drug for sale&period;<&sol;p>&NewLine;<p>Shares slumped as hopes are running high for the treatment&comma; which has already been approved in Europe and is designed to rival blockbuster Plavix&comma; the world&&num;8217&semi;s second biggest selling drug&period;<&sol;p>&NewLine;<p>But the group&&num;8217&semi;s shares shrugged off the news&comma; with AstraZeneca confirming the fourth quarter financial hit would not impact core earnings&period;<&sol;p>&NewLine;<p>Its decision to pull development of motavizumab has not come as a surprise to analysts after the drug hit troubles with the FDA in America&period;<&sol;p>&NewLine;<p>A US medical advisory panel cited concerns last June over potentially serious side effects&comma; while the FDA added to delays by issuing a second so-called complete response letter this August&period;<&sol;p>&NewLine;<p>However&comma; AstraZeneca confirmed motavizumab remains in development for other serious respiratory syncytial virus &lpar;RSV&rpar; treatment&period;<&sol;p>&NewLine;<p>AstraZeneca employs 11&comma;000 staff in the UK and has sites at Macclesfield and Wilmslow in Cheshire&comma; Luton&comma; Loughborough&comma; Edinburgh and Brixham in Devon&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed912b08c53">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; function &lpar;&rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;if &lpar; false &equals;&equals;&equals; &lpar; window&period;isWatlV1 &quest;&quest; 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