Blood plasma from Covid-19 survivors ‘improved symptoms of severely ill patients’

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>A single dose of antibodies drawn from the blood of Covid-19 survivors appears to have improved the symptoms of 10 patients severely ill with the disease&comma; according to new research&period;<&sol;p>&NewLine;<p>The treatment&comma; known as convalescent plasma &lpar;CP&rpar; therapy&comma; involves using antibody-rich blood plasma of those who have recovered from coronavirus&comma; which can neutralise the bug to fight infection&period;<&sol;p>&NewLine;<p>Scientists in China who conducted the preliminary study said no serious adverse reactions were observed after CP transfusion&period;<&sol;p>&NewLine;<p>They believe the findings&comma; published in the journal Proceedings of the National Academy of Sciences&comma; suggest that CP therapy might be a safe and promising treatment for severe Covid-19 patients&comma; and add further investigation is needed in controlled clinical trials&period;<&sol;p>&NewLine;<p>But experts have warned the results&comma; while encouraging&comma; should be treated with caution&period;<&sol;p>&NewLine;<p>Munir Pirmohamed&comma; president of the British Pharmacological Society&comma; said&colon; <em>&OpenCurlyDoubleQuote;This was not a randomised trial and all patients also received other treatments including antivirals such as remdesivir&comma; which are currently in trials for Covid-19&period;”<&sol;em><&sol;p>&NewLine;<p>He added that it was also important to remember that there are potential safety concerns around the treatment&comma; including diseases that occur through transfusion&period;<&sol;p>&NewLine;<p>Mr Pirmohamed said&colon;<em> &&num;8220&semi;Even if shown to work&comma; scalability to treat large numbers of patients may become an issue&period;&&num;8221&semi;<&sol;em><&sol;p>&NewLine;<p>The pilot study involved 10 patients&comma; aged between 34 and 78&comma; who showed severe symptoms such as shortness of breath and chest pain&period;<&sol;p>&NewLine;<p>The enrolled patients received transfusion of a 200ml dose of CP&period;<&sol;p>&NewLine;<p>The researchers said all clinical symptoms&comma; which also included fever and cough&comma; subsided within three days&period;<&sol;p>&NewLine;<p>The patients’ liver and lung function as well as blood oxygen levels were also found to have improved&period;<&sol;p>&NewLine;<p>The numbers of disease-fighting white blood cells&comma; lymphocytes&comma; also increased&comma; and antibody levels remained high after CP transfusion&comma; the researchers said&period;<&sol;p>&NewLine;<p>Meanwhile another study&comma; reported in the Journal of the American Medical Association last month&comma; showed that five critically ill coronavirus patients in Shenzen&comma; China&comma; improved after treatment with CP&period;<&sol;p>&NewLine;<p>The Food and Drug Administration in the US approved the use of CT therapy as an experimental treatment in clinical trials&comma; and for critical patients without other options&period;<&sol;p>&NewLine;<p>In the UK&comma; it has been reported that the NHS may start giving the therapy to hospital patients in the near future&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed9e4675418">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; function &lpar;&rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;if &lpar; false &equals;&equals;&equals; &lpar; window&period;isWatlV1 &quest;&quest; false &rpar; &rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&sol;&sol; Use Aditude scripts&period;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings &equals; window&period;tudeMappings &vert;&vert; &lbrack;&rsqb;&semi;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings&period;push&lpar; 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