Diabetes study reveals insulin levels stabilise after seven years

Diabetes study reveals insulin levels stabilise after seven years

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Diabetes, Blood, Insulin, Health

There is a “seven year switch” in people with Type 1 diabetes before insulin levels stabilise, scientists have revealed.

New research has shown that the rapid decline in insulin production, which causes Type 1 diabetes, continues to fall by almost 50% each year for seven years and then stabilizes.

Scientists at the University of Exeter said the findings were a major step forward in understanding Type 1 diabetes, and contradicts previous beliefs that the insulin produced by people with the condition drops relentlessly with time.

There is a “seven year switch” in people with Type 1 diabetes before insulin levels stabilise, scientists have revealed.

New research has shown that the rapid decline in insulin production, which causes Type 1 diabetes, continues to fall by almost 50% each year for seven years and then stabilises.

Scientists at the University of Exeter said the findings were a major step forward in understanding Type 1 diabetes, and contradicts previous beliefs that the insulin produced by people with the condition drops relentlessly with time.

Type 1 diabetes affects around 400,000 people in the UK.

The disease commonly starts in childhood ,but can develop at any age and causes the body’s own immune system to attack and destroy the insulin-producing cells in the pancreas – leaving the patient dependent on life-long insulin injections.

Professor Andrew Hattersley added: “Now we know there is a ‘seven year switch’, the next question is why?

“Has the immune attack stopped or are we left with ‘super beta-cells’ that can resist the immune onslaught.

“Any insights into halting the relentless destruction of the precious insulin-producing cells are valuable.”

– The study, C-peptide decline in type 1 diabetes has two phases: an initial exponential fall and a subsequent stable phase, is published in the journal Diabetes Care.

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