Fortnightly chemotherapy ‘gives better chance’ for breast cancer women under 50

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>Having chemotherapy every two weeks&comma; rather than three&comma; can improve survival chances for women under 50 with breast cancer&comma; new research suggests&period;<&sol;p>&NewLine;<p>The two-weekly therapy doesn’t seem to increase a woman’s risk of treatment-induced early menopause&comma; the researchers said&comma; meaning young women would suffer no greater cost to their fertility&period;<&sol;p>&NewLine;<p>The study&comma; to be presented to the European Breast Cancer Conference in Amsterdam&comma; analysed data from two large clinical trials that compared adjuvant chemotherapy given every two weeks&comma; known as a &OpenCurlyDoubleQuote;dose dense” regimen&comma; or every three weeks – the standard interval&period;<&sol;p>&NewLine;<p>A total of 3&comma;305 patients were included in both studies&comma; of whom 1&comma;549 were pre-menopausal with an average age of 44&period;<&sol;p>&NewLine;<p>The researchers found that the two-weekly chemotherapy significantly improved overall survival after 10 years by nearly a third compared with chemotherapy given at the standard interval of three weeks&period;<&sol;p>&NewLine;<p>Dr Matteo Lambertini&comma; a medical oncologist at the National Institute for Cancer Research in Genoa&comma; Italy&comma; will tell delegates&colon; &OpenCurlyDoubleQuote;The take-home message of our study is that dose-dense adjuvant chemotherapy is associated with a significant improvement in overall survival as compared to standard-interval chemotherapy in high-risk&comma; pre-menopausal breast cancer patients&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;This is very important information for counselling young patients regarding the choice among the available adjuvant chemotherapy regimens&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Chemotherapy remains a mainstay adjuvant treatment for the majority of young breast cancer patients&comma; but its psychosocial impact can be substantial&period;”<&sol;p>&NewLine;<p><a href&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2016&sol;03&sol;image-28&period;jpg" rel&equals;"attachment wp-att-87131"><img src&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2016&sol;03&sol;image-28-300x226&period;jpg" alt&equals;"image" width&equals;"300" height&equals;"226" class&equals;"alignright size-medium wp-image-87131" &sol;><&sol;a><&sol;p>&NewLine;<p>Katie Goates&comma; senior research communications officer at Breast Cancer Now&comma; said&colon; &OpenCurlyDoubleQuote;This promising study confirms that having chemotherapy every two weeks&comma; rather than three&comma; can improve the chance of survival for women with breast cancer under 50&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Additionally&comma; the findings reassuringly show that the increased survival seen with two-weekly chemotherapy doesn’t come at a greater cost to fertility&comma; something that is incredibly important for young women considering their treatment options&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;However&comma; the research also shows that two-weekly chemotherapy can increase the possibility of side-effects such as anaemia and muscle or bone pain&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;This serves as a critical reminder of the need to find treatments that improve both women’s chances of survival and their quality of life during treatment&period;”<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed5e3d1d8d3">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; 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