London patient second in world to be cleared of Aids virus – researchers

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>A London hospital patient is the second person in the world to be cleared of the Aids virus&comma; doctors have said&period;<&sol;p>&NewLine;<p>The male patient has achieved &OpenCurlyDoubleQuote;sustained remission” from HIV after being treated at Hammersmith Hospital in west London&comma; Imperial College Healthcare NHS Trust said&period;<&sol;p>&NewLine;<p>The case report&comma; led by researchers at UCL and Imperial College London&comma; comes around a decade after the first known case in Berlin&period;<&sol;p>&NewLine;<p>In 2003&comma; the male patient was diagnosed with HIV infection and developed an Aids defining cancer&comma; advanced Hodgkin’s Lymphoma&comma; in 2012&period;<&sol;p>&NewLine;<p>In 2016&comma; he received a transplant of haematopoietic stem cells from a donor carrying a genetic mutation in the HIV receptor CCR5&comma; which hinders the HIV virus from entering human cells&period;<&sol;p>&NewLine;<p>He has now been in remission for 18 months after his antiretroviral drugs were discontinued&comma; researchers said&period;<&sol;p>&NewLine;<p>We continue to monitor his condition&semi; however&comma; the apparent success of this treatment injects new hope in the search for a long-awaited cure for HIV&sol;Aids<&sol;p>&NewLine;<p>Professor Eduardo Olavarria&comma; from Imperial College London&comma; said&colon; &OpenCurlyDoubleQuote;While it is too premature to say with certainty that our patient is now cured of HIV&comma; he is clearly in a long-term remission&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;We continue to monitor his condition&semi; however&comma; the apparent success of this treatment injects new hope in the search for a long-awaited cure for HIV&sol;Aids&period;”<&sol;p>&NewLine;<p>Similar therapy has been successful once before with &OpenCurlyDoubleQuote;Berlin Patient”&comma; a US man treated in Germany 12 years ago who is still free of HIV&period;<&sol;p>&NewLine;<p>Timothy Ray Brown said he would like to meet the London patient and would encourage him to go public because &OpenCurlyDoubleQuote;it’s been very useful for science and for giving hope to HIV-positive people&comma; to people living with HIV”&period;<&sol;p>&NewLine;<p>The case was published online by the journal Nature and will be presented at an HIV conference in Seattle&period;<&sol;p>&NewLine;<p>The study’s lead author&comma; Professor Ravindra Gupta&comma; said&colon; &OpenCurlyDoubleQuote;Finding a way to eliminate the virus entirely is an urgent global priority&comma; but is particularly difficult because the virus integrates into the white blood cells of its host&period;”<&sol;p>&NewLine;<p>He added&colon; &OpenCurlyDoubleQuote;By achieving remission in a second patient using a similar approach&comma; we have shown that the Berlin Patient was not an anomaly&comma; and that it really was the treatment approaches that eliminated HIV in these two people&period;”<&sol;p>&NewLine;<p>The approach is not appropriate as a standard HIV treatment due to the toxicity of chemotherapy&comma; he warned&comma; but said he is &OpenCurlyDoubleQuote;hopeful” it will help them develop strategies that might eliminate HIV altogether&period;<&sol;p>&NewLine;<figure id&equals;"attachment&lowbar;127267" aria-describedby&equals;"caption-attachment-127267" style&equals;"width&colon; 600px" class&equals;"wp-caption aligncenter"><a href&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2019&sol;03&sol;51C36D77-5059-41AB-A6E8-ED4C4FF5B787&period;jpeg"><img class&equals;"size-full wp-image-127267" src&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2019&sol;03&sol;51C36D77-5059-41AB-A6E8-ED4C4FF5B787&period;jpeg" alt&equals;"" width&equals;"600" height&equals;"476" &sol;><&sol;a><figcaption id&equals;"caption-attachment-127267" class&equals;"wp-caption-text">Timothy Ray Brown&comma; known as the &OpenCurlyQuote;Berlin Patient&semi;&comma; was the first person to be cured of HIV infection<&sol;figcaption><&sol;figure>&NewLine;<p>Dr Michael Brady&comma; medical director at HIV charity Terrence Higgins Trust&comma; praised the breakthrough but said researchers were &OpenCurlyDoubleQuote;still some way off” from establishing a cure&period;<&sol;p>&NewLine;<p>He said&colon; &OpenCurlyDoubleQuote;But what we are able to say with certainty is that&comma; through early diagnosis and access to treatment&comma; you can live a long&comma; healthy life with HIV and be confident you won’t pass the virus to your sexual partners&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;With regular testing&comma; condoms&comma; pre-exposure prophylaxis &lpar;PrEP&rpar; and the fact that people on effective HIV treatment cannot pass on the virus&comma; we have the ability to completely prevent new HIV transmissions&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Today’s news is a welcome development for many people living with HIV&comma; but we must not take our eye off the ball in ensuring we use the tools we already have that can help us towards zero new transmissions&period;”<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ecf52dd048f">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; function &lpar;&rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;if &lpar; false &equals;&equals;&equals; &lpar; window&period;isWatlV1 &quest;&quest; false &rpar; &rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&sol;&sol; Use Aditude scripts&period;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings &equals; window&period;tudeMappings &vert;&vert; &lbrack;&rsqb;&semi;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings&period;push&lpar; 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