Researchers identify five different genetic types of prostate cancer

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>Five different recipes of prostate cancer have been identified&comma; with major implications for the way the disease is treated&period;<&sol;p>&NewLine;<p>The &OpenCurlyDoubleQuote;five ways” discovery was made by scientists who studied samples of healthy and cancerous tissue from more than 250 men&period;<&sol;p>&NewLine;<p>Tumours were grouped into five distinct categories based on the activity of 100 different genes&period;<&sol;p>&NewLine;<p>Each had a characteristic genetic fingerprint&comma; the study showed&period; The analysis was better at spotting deadly cancers than tests currently used by doctors&comma; including the PSA &lpar;Prostate Specific Antigen&rpar; blood marker and Gleason score aggressiveness rating&period;<&sol;p>&NewLine;<p>Lead researcher Dr Alastair Lamb&comma; from the Cancer Research UK Cambridge Institute&comma; said&colon; &OpenCurlyDoubleQuote;Our exciting results show that prostate cancer can be classified into five genetically-different types&period; These findings could help doctors decide on the best course of treatment for each individual patient&comma; based on the characteristics of their tumour&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;The next step is to confirm these results in bigger studies and drill down into the molecular ’nuts and bolts’ of each specific prostate cancer type&period; By carrying out more research in to how the different diseases behave we might be able to develop more effective ways to treat prostate cancer patients in the future&comma; saving more lives&period;”<&sol;p>&NewLine;<p>Each year around 41&comma;700 men in the UK are diagnosed with prostate cancer and 10&comma;800 die from the disease&period;<&sol;p>&NewLine;<p>Prostate cancer is the most common cancer in men in the UK&comma; with around 41&comma;700 cases diagnosed every year&period; There are around 10&comma;800 deaths from the disease each year in the UK&period;<&sol;p>&NewLine;<p>Professor Malcolm Mason&comma; Cancer Research UK’s prostate cancer expert&comma; said&colon; &OpenCurlyDoubleQuote;The challenge in treating prostate cancer is that it can either behave like a pussycat – growing slowly and unlikely to cause problems in a man’s lifetime &&num;8211&semi; or a tiger&comma; spreading aggressively and requiring urgent treatment&period; But at the moment we have no reliable way to distinguish them&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;This means that some men may get treatment they don’t need&comma; causing unnecessary side effects&comma; while others might benefit from more intensive treatment&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;This research could be game-changing if the results hold up in larger clinical trials and could give us better information to guide each man’s treatment – even helping us to choose between treatments for men with aggressive cancers&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Ultimately this could mean more effective treatment for the men who need it&comma; helping to save more lives and improve the quality of life for many thousands of men with prostate cancer&period;”<&sol;p>&NewLine;<p>The research is published in the online journal EBioMedicine&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed9f9b297d7">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; 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