Scientist behind gene editing claims second pregnancy under way

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>A Chinese researcher who claims to have helped make the world’s first genetically-edited babies has said a second pregnancy may be under way&period;<&sol;p>&NewLine;<p>The researcher&comma; He Jiankui of Shenzhen&comma; revealed the possible pregnancy as he made his first public comments about his controversial work at an international conference in Hong Kong&period; He claims to have altered the DNA of twin girls born earlier this month to try to make them resistant to infection with HIV&period;<&sol;p>&NewLine;<p>Mr He said&colon; &OpenCurlyDoubleQuote;They need this protection since a vaccine is not available&period;”<br &sol;>&NewLine;Mainstream scientists have condemned the experiment&comma; and universities and government groups are investigating&period; The second potential pregnancy is in a very early stage and needs more time to be monitored to see if it will last&comma; Mr He said&period;<&sol;p>&NewLine;<p>The conference leader called Mr He’s experiments &OpenCurlyDoubleQuote;irresponsible”&comma; and said it provided evidence that the scientific community had failed to regulate itself to prevent premature efforts to alter human DNA&period; The work is highly controversial because the changes can be inherited and could go on to harm other genes&comma; and is banned in many countries&period;<&sol;p>&NewLine;<figure id&equals;"attachment&lowbar;121346" aria-describedby&equals;"caption-attachment-121346" style&equals;"width&colon; 600px" class&equals;"wp-caption aligncenter"><a href&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2018&sol;11&sol;D4C57FFC-92ED-43B5-824B-ED9CC31AAB80&period;jpeg"><img src&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2018&sol;11&sol;D4C57FFC-92ED-43B5-824B-ED9CC31AAB80&period;jpeg" alt&equals;"" width&equals;"600" height&equals;"400" class&equals;"size-full wp-image-121346" &sol;><&sol;a><figcaption id&equals;"caption-attachment-121346" class&equals;"wp-caption-text">Mr He has faced strong criticism over the controversial move<&sol;figcaption><&sol;figure>&NewLine;<p>Jennifer Doudna&comma; a University of California-Berkeley scientist and one of the inventors of the CRISPR gene editing tool which Mr He claimed to have used&comma; said&colon; &OpenCurlyDoubleQuote;This is a truly unacceptable development&period;<br &sol;>&NewLine;&OpenCurlyDoubleQuote;I’m grateful that he appeared today&comma; but I don’t think that we heard answers&period; We still need to understand the motivation for this&period;”<&sol;p>&NewLine;<p>David Liu of Harvard and MIT’s Broad Institute&comma; the inventor of a variation of the gene editing tool&comma; said&colon; &OpenCurlyDoubleQuote;I feel more disturbed now&period; &OpenCurlyDoubleQuote;It’s an appalling example of what not to do about a promising technology that has great potential to benefit society&period; I hope it never happens again&period;”<&sol;p>&NewLine;<p>There is no independent confirmation of Mr He’s claim and he has not yet published in any scientific journal where his work would be vetted by experts&period;<&sol;p>&NewLine;<figure id&equals;"attachment&lowbar;121347" aria-describedby&equals;"caption-attachment-121347" style&equals;"width&colon; 600px" class&equals;"wp-caption aligncenter"><a href&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2018&sol;11&sol;DB39B6CF-8999-45AE-B2FA-8C715A449005&period;jpeg"><img src&equals;"https&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2018&sol;11&sol;DB39B6CF-8999-45AE-B2FA-8C715A449005&period;jpeg" alt&equals;"" width&equals;"600" height&equals;"400" class&equals;"size-full wp-image-121347" &sol;><&sol;a><figcaption id&equals;"caption-attachment-121347" class&equals;"wp-caption-text">Scientists claimed the case showed that self-regulation had failed<&sol;figcaption><&sol;figure>&NewLine;<p>At the conference&comma; Mr He failed or refused to answer many questions&comma; including&colon; who funded him&comma; how did he ensure that participants understood the potential risks and benefits&comma; and why did he keep his work secret until after it was done&quest;<&sol;p>&NewLine;<p>After Mr He spoke&comma; David Baltimore&comma; a Nobel laureate from the California Institute of Technology and a leader of the conference&comma; said the scientist’s work &OpenCurlyDoubleQuote;would still be considered irresponsible” because it did not meet criteria many scientists agreed on several years ago before gene editing could be considered&period;<&sol;p>&NewLine;<p>Mr Baltimore said&colon; &OpenCurlyDoubleQuote;I personally don’t think that it was medically necessary&period;”<br &sol;>&NewLine;The case shows &OpenCurlyDoubleQuote;there has been a failure of self-regulation by the scientific community” and said the conference committee would meet and issue a statement on Thursday about the future of the field&comma; Mr Baltimore added&period;<&sol;p>&NewLine;<p>Before Mr He’s talk&comma; Dr George Daley&comma; Harvard Medical School’s dean and one of the conference organisers&comma; warned against a backlash to gene editing because of Mr He’s experiment&period;<&sol;p>&NewLine;<p>Dr Daley said that just because the first case may have been a mis-step&comma; this &OpenCurlyDoubleQuote;should in no way&comma; I think&comma; lead us to stick our heads in the sand and not consider the very&comma; very positive aspects that could come forth by a more responsible pathway”&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Scientists who go rogue … it carries a deep&comma; deep cost to the scientific community&comma;” Dr Daley added&period;<br &sol;>&NewLine;Regulators have been swift to condemn the experiment as unethical and unscientific&period;<&sol;p>&NewLine;<p>China’s National Health Commission has ordered local officials in Guangdong province to investigate Mr He’s actions&comma; and his employer&comma; Southern University of Science and Technology of China&comma; is also investigating&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68e28e8e30a68">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; 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