Scientists closer to predicting development of breast cancer tumours

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"2">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>Scientists have moved a step closer to being able to predict the likelihood that very early tumours will develop into full-blown breast cancer&comma; according to new research&period;<&sol;p>&NewLine;<p>A team looking at the relationship between early breast cancer tumours and more advanced forms of the disease has discovered a potential way to separate patients according to their risk and offer tailored treatment as a result&period;<&sol;p>&NewLine;<p><a href&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2016&sol;04&sol;image-12&period;jpg" rel&equals;"attachment wp-att-88589"><img src&equals;"http&colon;&sol;&sol;londonglossy&period;com&sol;wp-content&sol;uploads&sol;2016&sol;04&sol;image-12&period;jpg" alt&equals;"image" width&equals;"600" height&equals;"400" class&equals;"aligncenter size-full wp-image-88589" &sol;><&sol;a><&sol;p>&NewLine;<p>The most common form of non-invasive&comma; or early&comma; breast cancer is ductal carcinoma in situ &lpar;DCIS&rpar; and occurs when cancer cells develop in the milk ducts but have not yet spread to the surrounding breast tissue&period;<&sol;p>&NewLine;<p>There are around 5&comma;000 cases diagnosed every year in the UK&comma; half of which it is estimated will develop into invasive breast cancer&period;<&sol;p>&NewLine;<p>Scientists at the Northern Ireland Molecular Pathology Laboratory at Queen’s University Belfast identified biomarkers which showed promise for predicting which cases were linked to invasive disease&comma; and potential treatments which could be used to target the biomarkers they found to be significantly associated with breast cancer&period;<&sol;p>&NewLine;<p>The study&comma; funded by Cancer Research UK&comma; could mean women with DCIS considered to be at a high risk of developing breast cancer would be offered more intensive treatment&period;<&sol;p>&NewLine;<p>Likewise those thought to be at a lower risk would be given the option to have more conservative treatment&period;<&sol;p>&NewLine;<p>Dr Richard Berks&comma; senior research communications officer at Breast Cancer Now&comma; said the research is vital to helping improve knowledge on which cases are likely to progress&period;<&sol;p>&NewLine;<p>He said&colon; &OpenCurlyDoubleQuote;What could happen from research like this in the future is that a patient might go to their doctor to get their DCIS checked out and if they find out there is a high chance that their tumour is going to become something life-threatening they can treat it&comma; but if it appears the DCIS is not going to progress they can monitor it without treatment&period;”<&sol;p>&NewLine;<p>Dr Niamh Buckley&comma; a Breast Cancer Now scientific fellow&comma; said the findings could lead to better breast cancer care&period;<&sol;p>&NewLine;<p>She said&colon; &OpenCurlyDoubleQuote;Increased knowledge of the molecular profile of non-invasive cancers can only serve to enhance our understanding of the disease and&comma; in an era of personalised medicine&comma; can only bring us closer to improving breast cancer care&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;Our findings require further validation through clinical trials but we believe that the use of biomarkers could pave the way to a significant improvement in the management of non-invasive breast cancer&period;”<&sol;p>&NewLine;<p>Dr Berks added&colon; &OpenCurlyDoubleQuote;It’s these types of studies that will feed in to the future development of a whole new generation of post-diagnosis testing that could tell a clinician exactly how to treat an individual patient to achieve the best possible outcome for them&period;”<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed166d7cae8">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; function &lpar;&rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;if &lpar; false &equals;&equals;&equals; &lpar; window&period;isWatlV1 &quest;&quest; false &rpar; &rpar; &lbrace;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&sol;&sol; Use Aditude scripts&period;&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;tudeMappings &equals; 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