Zika virus could become history as scientists uncover vaccines

&Tab;&Tab;<div class&equals;"wpcnt">&NewLine;&Tab;&Tab;&Tab;<div class&equals;"wpa">&NewLine;&Tab;&Tab;&Tab;&Tab;<span class&equals;"wpa-about">Advertisements<&sol;span>&NewLine;&Tab;&Tab;&Tab;&Tab;<div class&equals;"u top&lowbar;amp">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;<amp-ad width&equals;"300" height&equals;"265"&NewLine;&Tab;&Tab; type&equals;"pubmine"&NewLine;&Tab;&Tab; data-siteid&equals;"111265417"&NewLine;&Tab;&Tab; data-section&equals;"1">&NewLine;&Tab;&Tab;<&sol;amp-ad>&NewLine;&Tab;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;&Tab;<&sol;div>&NewLine;&Tab;&Tab;<&sol;div><p>Scientists in the US believe they have found not one&comma; but two vaccines that can provide complete protection from the Zika virus&period;<&sol;p>&NewLine;<p>They say human trials could start by the end of the year&comma; after being successfully carried out on mice&comma; bringing them yet another step closer to finding an effective vaccine for people&period;<&sol;p>&NewLine;<p>Experts at the Beth Israel Deaconess Medical Centre – part of Harvard Medical School&comma; the Walter Reed Army Institute of Research &lpar;WRAIR&rpar; and the University of Sao Paulo – found that mice given either of two jabs did not pick up Zika when they were exposed to it up to two months later&period;<&sol;p>&NewLine;<p>One of the jabs was a DNA vaccine based on a Zika virus strain isolated in Brazil&comma; while the other was a purified&comma; inactivated virus vaccine &lpar;meaning it was made non-functional&rpar; based on a Zika virus strain isolated in Puerto Rico&period;<&sol;p>&NewLine;<p>The study&comma; published in the journal Nature&comma; showed that single shots of either vaccine completely protected the mice against Zika&period;<&sol;p>&NewLine;<p>Colonel Stephen Thomas&comma; an infectious disease army doctor and head of the Zika vaccine programme at WRAIR&comma; said the institute could now develop a proper vaccine that builds on a type of vaccine that has been licensed before – and he is confident it will work&period;<&sol;p>&NewLine;<p>He said&colon; &OpenCurlyDoubleQuote;This critical first step has informed our ongoing work in non-human primates and gives us early confidence that development of a protective Zika virus vaccine for humans is feasible&period;”<&sol;p>&NewLine;<p>But it won’t be a simple transition from finding an effective vaccine for mice to developing one that will work for humans&period;<&sol;p>&NewLine;<p>Jonathan Ball&comma; professor of molecular virology at the University of Nottingham&comma; said&colon; &OpenCurlyDoubleQuote;On the face of it&comma; this is very good news and a significant step towards developing an effective vaccine to prevent Zika virus infection and the horrendous complications that this virus can sometimes cause&period;<&sol;p>&NewLine;<p>&OpenCurlyDoubleQuote;But we have to take these data in context&comma; these were mice experiments and there is a long way to go before you can be sure that this vaccine candidate will perform in humans&period;”<&sol;p>&NewLine;<p>The World Health Organisation &lpar;WHO&rpar; has declared Zika a global public health emergency and has warned it could spread to European holiday destinations this summer&period;<&sol;p>&NewLine;<p>Zika is spread by mosquitoes and causes severe brain defects in unborn children&period; It is also linked to the neurological condition Guillain-Barre syndrome&period;<&sol;p>&NewLine;&Tab;&Tab;&Tab;<div style&equals;"padding-bottom&colon;15px&semi;" class&equals;"wordads-tag" data-slot-type&equals;"belowpost">&NewLine;&Tab;&Tab;&Tab;&Tab;<div id&equals;"atatags-dynamic-belowpost-68ed0f0988151">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;<script type&equals;"text&sol;javascript">&NewLine;&Tab;&Tab;&Tab;&Tab;&Tab;&Tab;window&period;getAdSnippetCallback &equals; 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