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		</div><p><a href="http://londonglossy.com/wp-content/uploads/2010/12/astrazeneca-shares-slump-in-ftse.jpg"><img class="alignnone size-full" title="The FTSE 100 Index edged 4.8 points higher to 5885.7" src="http://londonglossy.com/wp-content/uploads/2010/12/min-astrazeneca-shares-slump-in-ftse.jpg" alt="The FTSE 100 Index edged 4.8 points higher to 5885.7"/></a></p>
<p>Shares in AstraZeneca have slumped in the FTSE 100 Index after US regulators dealt a blow to its hopes of approval for heart drug Brilinta.</p>
<p>The stock slumped 4% or 139p to 3014p as the US Food and Drug Administration said it wanted more information about a key study into the drug.</p>
<p>The mood was subdued for the rest of the London market as the FTSE 100 Index edged 4.8 points higher to 5885.7 in thin pre-Christmas trading.</p>
<p>Other fallers included BP, which dropped 3.4p to 466.6p, as investors spent a second session worrying about the impact US legal action over the Gulf of Mexico disaster will have on the company&#8217;s planned resumption of dividend payments.</p>
<p>Outside the top flight, shares in National Express and Punch Taverns made progress after trading updates from the pair impressed analysts.</p>
<p>Punch lifted 3p to 69.95p as it said its managed pub estate continued to make progress in the 16 weeks to December 11, despite the impact of weather.</p>
<p>And National Express surged 7.8p to 235p as it raised its profit hopes for the year after moves to revamp its bus network paid off earlier than expected.</p>
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