A total of 254 people with flu have died in the UK since September, the Government has said.
The figure is up on the 112 cases reported last week.
Of 214 cases where information was available, 195 deaths were associated with the H1N1 infection.
The HPA said that, despite the jump in deaths, rates of flu in the UK appeared to be declining.
GP visits and calls to NHS Direct relating to flu have decreased.
And the recording of deaths lags a week or two behind the period of peak flu activity.
The figures show a total of 418 patients with suspected flu are being treated in critical care, down from 661 last week.
Of these, 20 were under five, six were aged 5-15, 344 were aged 16-64 and 48 were over 65.
Of the 210 cases where information was available on age, seven deaths were of children under five, 11 of patients aged 5-14, 137 of those aged 15-64, and 55 of those aged 65 or over.