Britons returning from coronavirus-hit Wuhan in China will be put in quarantine for 14 days.
Officials are looking at taking passengers to a military base once they arrive home, the Department of Health said.
A flight is due to leave Wuhan in China on Thursday.
We are working hard to get British nationals back from Wuhan.
Public safety is the top priority.
Anyone who returns from Wuhan will be safely isolated for 14 days, with all neccessary medical attention.
— Matt Hancock (@MattHancock) January 29, 2020
Passengers may be asked to sign a contract before they board the plane saying they agree to being placed in quarantine.
Anyone who does not wish to sign could be asked to stay.
Around 200 British nationals are thought to be in the Chinese city.
Health Secretary Matt Hancock tweeted: “We are working hard to get British nationals back from Wuhan. Public safety is the top priority.
“Anyone who returns from Wuhan will be safely isolated for 14 days, with all necessary medical attention.”
The move comes after Britons returning to the UK expressed fury after being told they must “self-isolate” – while also making their own way home from the airport.
Previous advice from Public Health England (PHE) was for those returning to stay at home for 14 days.
But Britons due to board the flight back from Wuhan said they had been told by authorities to make their own way through the city to Wuhan airport, and once they land on British soil they are expected to make their own way home, potentially coming into contact with hundreds of people on the way.
Experts in China have said there is evidence that people could transmit the virus without showing any symptoms, although UK experts think the risk is low.
Kharn Lambert, whose grandmother Veronica Theobald, 81, from Lancaster, is booked on a flight leaving Wuhan on Thursday, told the PA news agency: “We are not sure what time the flight will leave yet. She got a seat almost straight away because of her condition.
“She is relieved, so am I, but she’s frustrated with the restrictions being put in place. She can only take 15kg of hand luggage and she came here with about 30kg of stuff.”
The family has not been given exact timings for the flight or details of which London airport Mrs Theobold will arrive at.
Mr Lambert has decided not to return, and will stay in Wuhan.